Electrocatalysis by subcellular liver fractions bound to carbon nanostructures for stereoselective green drug metabolite synthesis

Abstract

A novel, reusable, cofactor-free, and mediator-free human liver microsomal bioreactor constructed on carbon nanostructure electrodes for stereoselective green syntheses of drug metabolites and specialty chemicals is reported here for the first time. Drug metabolites are useful for examining pharmaceutical and pharmacological properties of new drugs under development.