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Issue 25, 2015
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Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids

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Abstract

We show that ethanol can induce the formation of water-permeable defects in model membranes of skin, providing a fresh perspective on ethanol as a membrane modulator. We rationalise our findings in terms of the chemical nature of ethanol, i.e., a combination of its hydrogen bonding propensity and amphiphilic character.

Graphical abstract: Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids

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Supplementary files

Article information


Submitted
28 Oct 2014
Accepted
23 Dec 2014
First published
23 Dec 2014

Chem. Commun., 2015,51, 5406-5409
Article type
Communication
Author version available

Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids

R. Thind, D. W. O'Neill, A. Del Regno and R. Notman, Chem. Commun., 2015, 51, 5406
DOI: 10.1039/C4CC08527B

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