Jump to main content
Jump to site search

Issue 24, 2015
Previous Article Next Article

Iodine promoted α-hydroxylation of ketones

Author affiliations

Abstract

A novel method for α-hydroxylation of ketones using substoichiometric amount of iodine under metal-free conditions is described. This method has been successfully employed in synthesizing a variety of heterocyclic compounds, which are useful precursors. α-Hydroxylation of diketones and triketones are illustrated. This strategy provides a novel, efficient, mild and inexpensive method for α-hydroxylation of aryl ketones using a sub-stoichiometric amount of molecular iodine.

Graphical abstract: Iodine promoted α-hydroxylation of ketones

Back to tab navigation

Supplementary files

Article information


Submitted
06 Apr 2015
Accepted
11 May 2015
First published
11 May 2015

Org. Biomol. Chem., 2015,13, 6749-6753
Article type
Paper
Author version available

Iodine promoted α-hydroxylation of ketones

Y. Siddaraju and K. R. Prabhu, Org. Biomol. Chem., 2015, 13, 6749 DOI: 10.1039/C5OB00684H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements