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Issue 9, 2015
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In situ nanofabrication of hybrid PEG-dendritic–inorganic nanoparticles and preliminary evaluation of their biocompatibility

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Abstract

An in situ template fabrication of inorganic nanoparticles using carboxylated PEG-dendritic block copolymers of the GATG family is described as a function of the dendritic block generation, the metal (Au, CdSe) and metal molar ratio. The biocompatibility of the generated nanoparticles analysed in terms of their aggregation in physiological media, cytotoxicity and uptake by macrophages relates to the PEG density of the surface of the hybrids.

Graphical abstract: In situ nanofabrication of hybrid PEG-dendritic–inorganic nanoparticles and preliminary evaluation of their biocompatibility

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Supplementary files

Article information


Submitted
18 Oct 2014
Accepted
07 Dec 2014
First published
08 Dec 2014

Nanoscale, 2015,7, 3933-3940
Article type
Paper
Author version available

In situ nanofabrication of hybrid PEG-dendritic–inorganic nanoparticles and preliminary evaluation of their biocompatibility

A. Sousa-Herves, C. Sánchez Espinel, A. Fahmi, Á. González-Fernández and E. Fernandez-Megia, Nanoscale, 2015, 7, 3933
DOI: 10.1039/C4NR06155A

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