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Issue 26, 2015
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Light sensitization of DNA nanostructures via incorporation of photo-cleavable spacers

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Abstract

Using light irradiation as a trigger, large-scale structural reconfiguration of DNA nanostructures is demonstrated. We incorporated photo-cleavable spacers at strategic locations within the short oligonucleotide strands connecting adjacent helices within a DNA origami sphere, and then used light to transform the sphere into two tethered hemispheres.

Graphical abstract: Light sensitization of DNA nanostructures via incorporation of photo-cleavable spacers

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Article information


Submitted
05 Jan 2015
Accepted
10 Feb 2015
First published
10 Feb 2015

Chem. Commun., 2015,51, 5747-5750
Article type
Communication
Author version available

Light sensitization of DNA nanostructures via incorporation of photo-cleavable spacers

R. E. Kohman and X. Han, Chem. Commun., 2015, 51, 5747
DOI: 10.1039/C5CC00082C

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