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Issue 15, 2015
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Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls

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Abstract

Salicylic acids are shown to be readily available and versatile starting materials that easily undergo a tandem arylation–protodecarboxylation process under Pd-catalysis. The corresponding meta-arylphenols can subsequently be easily transformed into a variety of meta-functionalized biaryls, highlighting the versatility of this approach to access this structural motif.

Graphical abstract: Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls

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Supplementary files

Article information


Submitted
03 Dec 2014
Accepted
07 Jan 2015
First published
09 Jan 2015

Chem. Commun., 2015,51, 3127-3130
Article type
Communication
Author version available

Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls

J. Luo, S. Preciado and I. Larrosa, Chem. Commun., 2015, 51, 3127
DOI: 10.1039/C4CC09674F

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