Issue 26, 2016

Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones

Abstract

The syntheses of β,β-diaryl aryl propiophenones have been realized via palladium-catalyzed domino reactions of dimethyl amino functionalized enaminones and aryl boronic acids. This is the first example of transition metal-catalyzed enaminone C–N bond conversion for the generation of a new C–C(aryl) structure.

Graphical abstract: Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones

Supplementary files

Article information

Article type
Paper
Submitted
12 May 2016
Accepted
26 May 2016
First published
26 May 2016

Org. Biomol. Chem., 2016,14, 6270-6273

Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones

S. Zhong, Y. Lu, Y. Zhang, Y. Liu and J. Wan, Org. Biomol. Chem., 2016, 14, 6270 DOI: 10.1039/C6OB01038E

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