Jump to main content
Jump to site search

Issue 13, 2015
Previous Article Next Article

Tuning macrocycles to design ‘turn-on’ fluorescence probes for manganese(ii) sensing in live cells

Author affiliations

Abstract

We tune the coordination environment of macrocyclic ligands to design two novel fluorescence sensors for Mn2+. The BODIPY-based Mn2+ sensor M1 affords an excellent, 52 fold, fluorescence ‘turn-on’ response despite the paramagnetic nature of Mn2+. The lipophilic probe is cell-permeable and confocal imaging demonstrates that the sensor distinctly detects Mn2+ within live cells.

Graphical abstract: Tuning macrocycles to design ‘turn-on’ fluorescence probes for manganese(ii) sensing in live cells

Back to tab navigation

Supplementary files

Article information


Submitted
29 Nov 2014
Accepted
23 Dec 2014
First published
23 Dec 2014

Chem. Commun., 2015,51, 2605-2608
Article type
Communication
Author version available

Tuning macrocycles to design ‘turn-on’ fluorescence probes for manganese(II) sensing in live cells

S. Bakthavatsalam, A. Sarkar, A. Rakshit, S. Jain, A. Kumar and A. Datta, Chem. Commun., 2015, 51, 2605
DOI: 10.1039/C4CC09542A

Social activity

Search articles by author

Spotlight

Advertisements