Re and 99mTc complexes of BodP3 – multi-modality imaging probes

Laura H. Davies; Benjamin B. Kasten; Paul D. Benny; Rory L. Arrowsmith; Haobo Ge; Sofia I. Pascu; Stan W. Botchway; William Clegg; Ross W. Harrington; Lee J. Higham

doi:10.1039/C4CC06367H

Re and ^99mTc complexes of BodP₃ – multi-modality imaging probes†

Laura H. Davies,^a Benjamin B. Kasten,^b Paul D. Benny,*^b Rory L. Arrowsmith,^c Haobo Ge,^c Sofia I. Pascu,*^c Stan W. Botchway,^d William Clegg,^a Ross W. Harrington^a and Lee J. Higham*^a

Author affiliations

* Corresponding authors

^a School of Chemistry, Newcastle University, Bedson Building, Newcastle upon Tyne, UK
E-mail: lee.higham@ncl.ac.uk

^b Department of Chemistry, Washington State University, Pullman, USA

^c Chemistry Department, University of Bath, Bath, UK

^d Central Laser Facility, STFC, Rutherford Appleton Laboratory, Harwell Science and Innovation Campus, Oxfordshire, UK

Abstract

A fluorescent tridentate phosphine, BodP₃ (2), forms rhenium complexes which effectively image cancer cells. Related technetium analogues are also readily prepared and have potential as dual SPECT/fluorescent biological probes.

Chemical Communications

Re and ^99mTc complexes of BodP₃ – multi-modality imaging probes†

Abstract

Supplementary files

Article information

Download Citation

Author version available

Permissions

Re and ^99mTc complexes of BodP₃ – multi-modality imaging probes

Social activity

Search articles by author

Spotlight

Advertisements

Chemical Communications