Electrochemical device based on a Pt nanosphere-paper working electrode for in situ and real-time determination of the flux of H2O2 releasing from SK-BR-3 cancer cells

Fang Liu; Shenguang Ge; Jinghua Yu; Mei Yan; Xianrang Song

doi:10.1039/C4CC04199B

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Electrochemical device based on a Pt nanosphere-paper working electrode for in situ and real-time determination of the flux of H₂O₂ releasing from SK-BR-3 cancer cells†

Fang Liu,^a Shenguang Ge,^a Jinghua Yu,

*^a Mei Yan^a and Xianrang Song^b

Author affiliations

* Corresponding authors

^a Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, University of Jinan, Jinan 250022, P. R. China
E-mail: ujn.yujh@gmail.com
Fax: +86-531-82765969
Tel: +86-531-82767161

^b Cancer Research Center, Shandong Tumor Hospital, Jinan 250117, P. R. China
E-mail: sxr@vip.163.com

Abstract

A novel paper working electrode with Pt nanospheres grown in it (Pt-PWE) was first used as a sensor platform and then cancer cells were immobilized on the Pt-PWE (high affinity binding with aptamers). This electrode was first designed to achieve the in situ and real-time determination of H₂O₂ released from cancer cells to obtain an accurate determination.

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Article information

DOI: https://doi.org/10.1039/C4CC04199B
Article type: Communication
Submitted: 02 Jun 2014
Accepted: 13 Jul 2014
First published: 14 Jul 2014

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Chem. Commun., 2014,50, 10315-10318

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Electrochemical device based on a Pt nanosphere-paper working electrode for in situ and real-time determination of the flux of H₂O₂ releasing from SK-BR-3 cancer cells

F. Liu, S. Ge, J. Yu, M. Yan and X. Song, Chem. Commun., 2014, 50, 10315 DOI: 10.1039/C4CC04199B

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Chemical Communications