Issue 15, 2014

Versatile ruthenium(ii)-catalyzed C–H cyanations of benzamides


Direct cyanations of arenes and heteroarenes bearing only weakly coordinating amides were accomplished using a robust ruthenium(II) catalyst. The user-friendly C(sp2)–H activation occurred with the assistance of carboxylate with high site-selectivity, excellent functional group tolerance and ample scope.

Graphical abstract: Versatile ruthenium(ii)-catalyzed C–H cyanations of benzamides

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Article information

Article type
15 Dec 2013
02 Jan 2014
First published
06 Jan 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 1878-1881

Versatile ruthenium(II)-catalyzed C–H cyanations of benzamides

W. Liu and L. Ackermann, Chem. Commun., 2014, 50, 1878 DOI: 10.1039/C3CC49502G

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