Towards the potential use of 1H NMR spectroscopy in urine samples for prostate cancer detection†
Abstract
A simple method based in multivariate analysis of 1H NMR spectra profiles of urine samples can be used to detect patients with prostate cancer.
* Corresponding authors
a Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universitat Politècnica de València – Universitat de València, Valencia, Spain
b
Servicio de Urología, Hospital Universitario y Politécnico La Fe, Valencia, Spain
E-mail:
Jose.L.Ruiz@uv.es
c Leitat Technological Center, Bio in vitro Division, Valencia, Spain
d Departamento de Química Orgánica, Facultad de Químicas, Universidad de Valencia, Doctor Moliner 50, 46100 Burjassot, Valencia, Spain
e Unidad Analítica, Instituto de Investigación Sanitaria – Fundación Hospital La Fe, Valencia, Spain
f Departamento de Proyectos de Ingeniería, Universitat Politècnica de València, Camino de Vera s/n., 46022 Valencia, Spain
g CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BNN), Spain
h
Departamento de Química, Universitat Politècnica de València, Camino de Vera s/n., 46022 Valencia, Spain
E-mail:
rmaez@qim.upv.es
A simple method based in multivariate analysis of 1H NMR spectra profiles of urine samples can be used to detect patients with prostate cancer.
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P. Zaragozá, J. L. Ruiz-Cerdá, G. Quintás, S. Gil, A. M. Costero, Z. León, J. Vivancos and R. Martínez-Máñez, Analyst, 2014, 139, 3875 DOI: 10.1039/C4AN00690A
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