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Issue 27, 2014
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Preparation and enzymatic application of flower-like hybrid microcapsules through a biomimetic mineralization approach

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Abstract

Fast and quantitative adsorption of molecules may confer hybrid microcapsules high performance in specific applications, such as biocatalysis, biosensing, drug delivery, and so on. Engineering the chemical/topological structures of the capsule wall renders great potential to achieve this goal. In the present study, flower-like microcapsules are prepared through a biomimetic mineralization approach. Briefly, protein-hybrid microflowers are firstly synthesized through enzyme-induced precipitation of Cu3(PO4)2, which are subsequently utilized as templates for alternative deposition of the protamine layer and the silica layer through biomimetic silicification assisted by layer-by-layer (LbL) assembly. After treatment with EDTA, the flower-like protamine/silica hybrid (FPSH) microcapsules are obtained. Additionally, the hybrid capsule wall also endows the FPSH microcapsules with desirable pH, temperature and storage stability. Hopefully, our approach may provide a promising alternative to increase the efficiency of catalysis, drug delivery, etc.

Graphical abstract: Preparation and enzymatic application of flower-like hybrid microcapsules through a biomimetic mineralization approach

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Supplementary files

Article information


Submitted
31 Mar 2014
Accepted
30 Apr 2014
First published
01 May 2014

J. Mater. Chem. B, 2014,2, 4289-4296
Article type
Paper

Preparation and enzymatic application of flower-like hybrid microcapsules through a biomimetic mineralization approach

J. Shi, S. Zhang, X. Wang, C. Yang and Z. Jiang, J. Mater. Chem. B, 2014, 2, 4289
DOI: 10.1039/C4TB00507D

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