Rathinam K. Sankar, Rohan S. Kumbhare, Allimuthu T. Dharmaraja and Harinath Chakrapani
Chem. Commun., 2014,50, 15323-15326
DOI:
10.1039/C4CC07343F,
Communication
A thiol-selective 2-methyl-3-phenacrylate scaffold with spatiotemporal control over delivery of a cargo is reported. The half-lives of decomposition could be tuned from 30 min to 1 day and the scaffold's utility in thiol-inducible fluorophore release in cell-free as well as within cells is demonstrated.