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Issue 56, 2014
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Microwave-assisted preparation of nucleoside-phosphoramidites

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Abstract

Microwave-assisted phosphitylation of sterically hindered nucleosides is demonstrated to be an efficient method for the preparation of corresponding phosphoramidites (otherwise onerous under standard conditions) and is shown to be general in its applicability.

Graphical abstract: Microwave-assisted preparation of nucleoside-phosphoramidites

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Supplementary files

Article information


Submitted
25 Apr 2014
Accepted
16 May 2014
First published
16 May 2014

Chem. Commun., 2014,50, 7463-7465
Article type
Communication
Author version available

Microwave-assisted preparation of nucleoside-phosphoramidites

G. Meher, T. Efthymiou, M. Stoop and R. Krishnamurthy, Chem. Commun., 2014, 50, 7463
DOI: 10.1039/C4CC03092C

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