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Issue 21, 2013
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Enhanced fluorescence quenching of hemin detected by a novel polymer of curcumin

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Abstract

In this study, a novel polymer of curcumin is synthesized by sulfonation and the incorporation of aliphatic groups to the polymeric structure. It undergoes efficient fluorescence quenching in the presence of hemin and acts as a selective biosensor for the latter. The quenching efficiency increases significantly, up to 90.82% at a maximum of 100 μM concentration of hemin and at λex of 410 nm. The high zeta potential of the polymer (−98 mV) decreases to −38 mV at 100 μM concentration of hemin, which confirms the transfer of electron density from the polymer to the quencher during fluorescence quenching.

Graphical abstract: Enhanced fluorescence quenching of hemin detected by a novel polymer of curcumin

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Publication details

The article was received on 31 Jan 2013, accepted on 03 Apr 2013 and first published on 03 Apr 2013


Article type: Communication
DOI: 10.1039/C3RA40549D
RSC Adv., 2013,3, 7747-7750

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    Enhanced fluorescence quenching of hemin detected by a novel polymer of curcumin

    B. Gogoi and N. S. Sarma, RSC Adv., 2013, 3, 7747
    DOI: 10.1039/C3RA40549D

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