Lite Version|Standard version

To gain access to this content please
Log in via your home Institution.
Log in with your member or subscriber username and password.
Download

A highly efficient palladium-catalyzed carbenoid based N–H bond insertion has been developed. The α-amino esters were obtained in high isolated yields. Moreover, by choosing a suitable chiral auxiliary, stereoselective Pd-catalyzed N–H insertion has been realized. The chiral α-amino esters were obtained in high yields (up to 91%) and with excellent diastereoselectivities (d.r. > 19 : 1).

Graphical abstract: Palladium-catalyzed carbenoid based N–H bond insertions: application to the synthesis of chiral α-amino esters

Page: ^ Top