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Issue 22, 2013
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Functionalised TiO2nanoparticles deliver oligo-histidine and avidin tagged biomolecules simultaneously into the cell

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Abstract

The development of multifunctional, biocompatible nanoparticles is essential for delivering drugs and biomolecules into the cell. Here, we have functionalised TiO2 nanoparticles with tris-(nitrilo trisacetic acid) (Tris-NTA) and biotin, by covalent surface functionalisation. This biocompatible nanoparticle is non-cytotoxic and can deliver both oligo-histidine and avidin conjugated biomolecules simultaneously into the cell.

Graphical abstract: Functionalised TiO2 nanoparticles deliver oligo-histidine and avidin tagged biomolecules simultaneously into the cell

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Supplementary files

Article information


Submitted
05 Mar 2013
Accepted
11 Apr 2013
First published
12 Apr 2013

RSC Adv., 2013,3, 8215-8219
Article type
Communication

Functionalised TiO2 nanoparticles deliver oligo-histidine and avidin tagged biomolecules simultaneously into the cell

B. Jana, G. Mondal, A. Biswas, I. Chakraborty and S. Ghosh, RSC Adv., 2013, 3, 8215 DOI: 10.1039/C3RA41068D

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