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Issue 19, 2013
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Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor

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Abstract

We describe an electrochemical analog of fluorescence polarization that supports the quantitative measurement of a specific protein, the chemokine IP-10, directly in undiluted blood serum. The sensor is label-free, wash-free, and electronic, suggesting it could support point-of-care detection of diagnostic proteins in largely unprocessed clinical samples.

Graphical abstract: Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor

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Supplementary files

Article information


Submitted
29 May 2013
Accepted
23 Jul 2013
First published
25 Jul 2013

Analyst, 2013,138, 5580-5583
Article type
Communication

Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor

A. J. Bonham, N. G. Paden, F. Ricci and K. W. Plaxco, Analyst, 2013, 138, 5580
DOI: 10.1039/C3AN01079A

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