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Abstract | Cited by

The first Ritter reaction of 3-substituted 3-hydroxyoxindoles with nitriles, catalyzed by HClO4, is developed, which enables the synthesis of 3-substituted 3-aminooxindoles in good to excellent yield with rich diversity.

Graphical abstract: A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles

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