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Issue 16, 2012
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A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles

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Abstract

The first Ritter reaction of 3-substituted 3-hydroxyoxindoles with nitriles, catalyzed by HClO4, is developed, which enables the synthesis of 3-substituted 3-aminooxindoles in good to excellent yield with rich diversity.

Graphical abstract: A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles

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Publication details

The article was received on 13 Feb 2012, accepted on 05 Mar 2012 and first published on 05 Mar 2012


Article type: Communication
DOI: 10.1039/C2OB25319D
Org. Biomol. Chem., 2012,10, 3178-3181

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    A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles

    F. Zhou, M. Ding and J. Zhou, Org. Biomol. Chem., 2012, 10, 3178
    DOI: 10.1039/C2OB25319D

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