Issue 4, 2012
From the journal:

New Journal of Chemistry

Friedländer synthesis of polysubstituted quinolines and naphthyridines promoted by propylphosphonic anhydride (T3P®) under mild conditions†

Mouhamad Jida*ab  and  Benoit Deprezab  

* Corresponding authors

a Biostructures and Drug Discovery, INSERM U761, Faculté de Pharmacie, Université Lille Nord de France, 3 rue du Pr Laguesse, Lille F-59006, France
E-mail: mhmd_jida@yahoo.com
Tel: +33 640607000

b PRIM Pôle de Recherche Interdisciplinaire sur le Médicament, 3 rue du Pr Laguesse, Lille F-59006, France
Web: www.drugdiscoverylille.org

Abstract

A new convenient, efficient and environmentally eco-friendly protocol for Friedländer synthesis of polysubstituted quinolines and naphthyridines is described. A wide variety of new products were readily prepared in the presence of propylphosphonic anhydride (T3P®) in short reaction times and excellent yields under mild conditions.

Graphical abstract: Friedländer synthesis of polysubstituted quinolines and naphthyridines promoted by propylphosphonic anhydride (T3P®) under mild conditions

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Article information

DOI
https://doi.org/10.1039/C2NJ21043F
Article type
Letter
Submitted
16 Dec 2011
Accepted
13 Feb 2012
First published
27 Feb 2012

New J. Chem., 2012,36, 869-873

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Friedländer synthesis of polysubstituted quinolines and naphthyridines promoted by propylphosphonic anhydride (T3P®) under mild conditions

M. Jida and B. Deprez, New J. Chem., 2012, 36, 869 DOI: 10.1039/C2NJ21043F

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