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Issue 41, 2012
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Highly luminescent CuInS2–ZnS nanocrystals: achieving phase transfer and nuclear homing property simultaneously through simple TTAB modification

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Abstract

Monodisperse CuInS2–ZnS nanocrystals were synthesized in organic solvents and effectively transferred to aqueous phase with the aid of trimethyl(tetradecyl)ammonium bromide (TTAB). TTAB-stabilized CuInS2–ZnS (CIS–ZnS–TTAB) nanocomposites exhibited good aqueous stability and preserved the high luminescence of the nanocrystals after phase transfer. More intriguingly, without any further modification, CIS–ZnS–TTAB showed a striking nuclear homing property, preferentially accumulating in the nuclei of living cells. This novel probe CIS–ZnS–TTAB may have applications in nuclear selective imaging and as a multifunctional drug carrier for nuclear targeted drug delivery. Our work provides a simple but effective way for hydrophobic nanomaterials to achieve both phase transfer and nuclear selectivity simultaneously.

Graphical abstract: Highly luminescent CuInS2–ZnS nanocrystals: achieving phase transfer and nuclear homing property simultaneously through simple TTAB modification

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Supplementary files

Article information


Submitted
07 Aug 2012
Accepted
29 Aug 2012
First published
30 Aug 2012

J. Mater. Chem., 2012,22, 21979-21986
Article type
Paper

Highly luminescent CuInS2–ZnS nanocrystals: achieving phase transfer and nuclear homing property simultaneously through simple TTAB modification

M. Wang, X. Liu, C. Cao and L. Wang, J. Mater. Chem., 2012, 22, 21979
DOI: 10.1039/C2JM35261C

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