Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 47, 2012
Previous Article Next Article

Planar SERS nanostructures with stochastic silver ring morphology for biosensor chips

Author affiliations


Surface-enhanced Raman spectroscopy (SERS) of living cells has rapidly become a powerful trend in biomedical diagnostics. It is a common belief that highly ordered, artificially engineered substrates are the best future decision in this field. This paper, however, describes an alternative successful solution, a new effortless chemical approach to the design of nanostructured silver and heterometallic continuous coatings with a stochastic “coffee ring” morphology. The coatings are formed from an ultrasonic mist of aqueous diamminesilver hydroxide, free of reducing agents and nonvolatile pollutants, under mild conditions, at about 200–270 °C in air. They consist of 30–100 micrometer wide and 100–400 nm high silver rings composed, in turn, of a porous silver matrix with 10–50 nm silver grains decorating the sponge. This hierarchic structure originates from ultrasonic droplet evaporation, contact-line motion, silver(I) oxide decomposition and evolution of a growing ensemble of silver rings. The fabricated substrates are a remarkable example of a new scalable and low cost material suitable for SERS analyses of living cells. They evoke no hemolysis and reduce erythrocyte lateral mobility due to suitable “coffee ring” sizes and a tight contact with the silver nanostructure. A high SERS enhancement, characteristic of pure silver rings, made it possible to record Raman scattering spectra from submembrane hemoglobin in its natural cellular environment inside single living erythrocytes, thus making the substrates promising for various biosensor chips.

Graphical abstract: Planar SERS nanostructures with stochastic silver ring morphology for biosensor chips

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Jul 2012, accepted on 27 Sep 2012 and first published on 27 Sep 2012

Article type: Paper
DOI: 10.1039/C2JM34686A
Citation: J. Mater. Chem., 2012,22, 24530-24544

  •   Request permissions

    Planar SERS nanostructures with stochastic silver ring morphology for biosensor chips

    A. A. Semenova, E. A. Goodilin, N. A. Brazhe, V. K. Ivanov, A. E. Baranchikov, V. A. Lebedev, A. E. Goldt, O. V. Sosnovtseva, S. V. Savilov, A. V. Egorov, A. R. Brazhe, E. Y. Parshina, O. G. Luneva, G. V. Maksimov and Y. D. Tretyakov, J. Mater. Chem., 2012, 22, 24530
    DOI: 10.1039/C2JM34686A

Search articles by author