A FRET-based probe with a chemically deactivatable quencher†
Abstract
A new concept of a chemically deactivatable quencher is proposed for a FRET-based probe that turns-on its fluorescence by either an enzymatic cleavage or a chemical reagent (
* Corresponding authors
a
Laboratory of Functional Chemo-Systems UMR 7199, 74 Route du Rhin, Illkirch, France
E-mail:
wagner@bioorga.u-strasbg.fr
Fax: +33 368854306
b Laboratoire de Pharmacologie et Physicochimie, UMR 7213 CNRS, 74 Route du Rhin, Illkirch, France
c PhytoDia SAS, Boulevard Sébastien Brant, 67412 Illkirch, France
A new concept of a chemically deactivatable quencher is proposed for a FRET-based probe that turns-on its fluorescence by either an enzymatic cleavage or a chemical reagent (
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