Issue 26, 2012
From the journal:

Chemical Communications

A disulfide bound-molecular beacon as a fluorescent probe for the detection of reduced glutathione and its application in cells†

Yingshu Guo,*a   Hao Wang,a   Yuanshun Suna  and  Bin Qua  

* Corresponding authors

a State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
E-mail: yingshug@126.com
Fax: +86-532-84022750
Tel: +86-532-84022946

Abstract

A disulfide-bound molecular beacon (MB) is reported to respond sensitively to changing levels of glutathionein vitro. Importantly, this successful application of a MB has exciting potential for monitoring cellular thiol.

Graphical abstract: A disulfide bound-molecular beacon as a fluorescent probe for the detection of reduced glutathione and its application in cells

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Article information

DOI
https://doi.org/10.1039/C2CC17552E
Article type
Communication
Submitted
03 Dec 2011
Accepted
06 Feb 2012
First published
06 Feb 2012

Chem. Commun., 2012,48, 3221-3223

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A disulfide bound-molecular beacon as a fluorescent probe for the detection of reduced glutathione and its application in cells

Y. Guo, H. Wang, Y. Sun and B. Qu, Chem. Commun., 2012, 48, 3221 DOI: 10.1039/C2CC17552E

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