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Issue 10, 2012
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Hyperbranched polymers for molecular imaging: designing polymers for parahydrogen induced polarisation (PHIP)

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Abstract

The first hyperpolarisation of polymers using parahydrogen induced polarisation (PHIP) is reported by hydrogenation of terminal alkyne groups in a biocompatible hyperbranched polymer. Signal enhancements of 1500-fold could be obtained depending on the structure of the polymer, thus opening new potential avenues for polymeric molecular imaging.

Graphical abstract: Hyperbranched polymers for molecular imaging: designing polymers for parahydrogen induced polarisation (PHIP)

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Publication details

The article was received on 30 Sep 2011, accepted on 06 Oct 2011 and first published on 17 Oct 2011


Article type: Communication
DOI: 10.1039/C1CC16077J
Citation: Chem. Commun., 2012,48, 1583-1585

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    Hyperbranched polymers for molecular imaging: designing polymers for parahydrogen induced polarisation (PHIP)

    K. Münnemann, M. Kölzer, I. Blakey, A. K. Whittaker and K. J. Thurecht, Chem. Commun., 2012, 48, 1583
    DOI: 10.1039/C1CC16077J

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