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Issue 10, 2012
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A nanocrystal-based ratiometric pH sensor for natural pH ranges

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Abstract

A ratiometric fluorescent pH sensor based on CdSe/CdZnS nanocrystal quantum dots (NCs) has been designed for biological pH ranges. The construct is formed from the conjugation of a pH dye (SNARF) to NCs coated with a poly(amido amine) (PAMAM) dendrimer. The sensor exhibits a well-resolved ratio response at pH values between 6 and 8 under linear or two-photon excitation, and in the presence of a 4% bovine serum albumin (BSA) solution.

Graphical abstract: A nanocrystal-based ratiometric pH sensor for natural pH ranges

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Supplementary files

Article information


Submitted
21 Feb 2012
Accepted
22 Jun 2012
First published
26 Jun 2012

Chem. Sci., 2012,3, 2980-2985
Article type
Edge Article

A nanocrystal-based ratiometric pH sensor for natural pH ranges

R. C. Somers, R. M. Lanning, P. T. Snee, A. B. Greytak, R. K. Jain, M. G. Bawendi and D. G. Nocera, Chem. Sci., 2012, 3, 2980 DOI: 10.1039/C2SC20212C

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