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Issue 2, 2012
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Facile glycosylation of dendrimers for eliciting specific cell–material interactions

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Abstract

Taking advantage of the reactivity between reducing glycans and hydrazides, a facile and general approach is demonstrated to conjugate glycan epitopes to polyamidoamine (PAMAM) based dendrimers. Using HepG2 cells, it is shown that parallel studies of different glycodendrimers allowed comparison and identification of multivalent conjugates with specific cell-binding capabilities.

Graphical abstract: Facile glycosylation of dendrimers for eliciting specific cell–material interactions

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Publication details

The article was received on 08 Sep 2011, accepted on 11 Nov 2011 and first published on 29 Nov 2011


Article type: Communication
DOI: 10.1039/C1PY00404B
Polym. Chem., 2012,3, 310-313

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    Facile glycosylation of dendrimers for eliciting specific cell–material interactions

    X. Liu, J. Liu and Y. Luo, Polym. Chem., 2012, 3, 310
    DOI: 10.1039/C1PY00404B

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