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Issue 1, 2012
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Advances in metal–carbene complexes as potent anti-cancer agents

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Abstract

This critical review is an updated survey of metal–carbenes as potential anticancer chemotherapeutics. We report on the recent advances in the discovery of N-heterocyclic carbenes, acyclic diamino carbenes and abnormal NHCs associated with metals from groups 10 and 11 that displayed antiproliferative activity and emphasize, when possible, their molecular target(s) and their mechanism of action.

Graphical abstract: Advances in metal–carbene complexes as potent anti-cancer agents

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Publication details

The article was received on 02 Aug 2011, accepted on 06 Oct 2011 and first published on 25 Oct 2011


Article type: Critical Review
DOI: 10.1039/C1MT00123J
Metallomics, 2012,4, 23-32

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    Advances in metal–carbene complexes as potent anti-cancer agents

    A. Gautier and F. Cisnetti, Metallomics, 2012, 4, 23
    DOI: 10.1039/C1MT00123J

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