Nagendra K. Sharma and Krishna N. Ganesh
Org. Biomol. Chem., 2011,9, 725-729
DOI:
10.1039/C0OB00528B,
Paper
Nucleic (DNA) acids having contiguous stretch of G sequence form quadruplex structure, which is very critical to control cell division. Recently the existence of G-quadruplex in RNA is also reported in presence of monovalent metal ion. PNA is a promising DNA analogue which binds strongly to DNA to form PNA : DNA duplex or PNA2 : DNA triplex. PNA also forms quadruplexes such G-quadruplex and i-motif in G and C-rich sequences respectively. aep-PNA containing a