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Issue 3, 2011
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P1,P2-Diimidazolyl derivatives of pyrophosphate and bis-phosphonates – synthesis, properties, and use in preparation of dinucleoside tetraphosphates and analogs

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Abstract

P 1,P2-Diimidazolyl derivatives of pyrophosphate and halomethylene-bis-phosphonates have been synthesized and characterized, and the mechanism of their formation was studied. These reagents enable synthesis of dinucleoside tetraphosphates and tetraphosphonates conveniently and in high yields.

Graphical abstract: P 1,P2-Diimidazolyl derivatives of pyrophosphate and bis-phosphonates – synthesis, properties, and use in preparation of dinucleoside tetraphosphates and analogs

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Article information


Submitted
05 Aug 2010
Accepted
29 Sep 2010
First published
17 Nov 2010

Org. Biomol. Chem., 2011,9, 730-738
Article type
Paper

P 1,P2-Diimidazolyl derivatives of pyrophosphate and bis-phosphonates – synthesis, properties, and use in preparation of dinucleoside tetraphosphates and analogs

I. B. Yanachkov, E. J. Dix, M. I. Yanachkova and G. E. Wright, Org. Biomol. Chem., 2011, 9, 730
DOI: 10.1039/C0OB00542H

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