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Issue 26, 2011
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From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

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Abstract

Thermodynamic control over kinetically-trapped mixtures of hydrazone-based macrocycles is achieved by addition of an aromatic monohydrazide to generate dynamic combinatorial libraries (DCLs) of linear and macrocyclic oligomers.

Graphical abstract: From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

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Publication details

The article was received on 19 Apr 2011, accepted on 18 May 2011 and first published on 03 Jun 2011


Article type: Communication
DOI: 10.1039/C1CC12268A
Citation: Chem. Commun., 2011,47, 7359-7361

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    From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

    S. R. Beeren, M. Pittelkow and J. K. M. Sanders, Chem. Commun., 2011, 47, 7359
    DOI: 10.1039/C1CC12268A

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