Issue 23, 2011
From the journal:

Chemical Communications

Active thionium species mediated functionalization at the 2α-position of indole derivatives†

Kazuhiro Higuchi,a   Masanori Tayua  and  Tomomi Kawasaki*a  

* Corresponding authors

a Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan
E-mail: kawasaki@my-pharm.ac.jp
Fax: +81 42 495 8763
Tel: +81 42 495 8763

Abstract

A combination of dimethyl sulfoxide (DMSO) and trifluoroacetic anhydride (TFAA) mediates functionalization at the 2α-position of indole derivatives. Carbon and heteroatom nucleophiles were directly introduced via a one-pot procedure in excellent yields.

Graphical abstract: Active thionium species mediated functionalization at the 2α-position of indole derivatives

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC11645B
Article type
Communication
Submitted
22 Mar 2011
Accepted
26 Apr 2011
First published
10 May 2011

Chem. Commun., 2011,47, 6728-6730

Permissions

Request permissions

Active thionium species mediated functionalization at the 2α-position of indole derivatives

K. Higuchi, M. Tayu and T. Kawasaki, Chem. Commun., 2011, 47, 6728 DOI: 10.1039/C1CC11645B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements