Issue 12, 2011
From the journal:

Chemical Communications

Recording force events of single quantum-dot endocytosis†

Yuping Shan,ac   Xian Hao,ac   Xin Shang,a   Mingjun Cai,a   Junguang Jiang,a   Zhiyong Tang*b  and  Hongda Wang*a  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P.R. China
E-mail: hdwang@ciac.jl.cn

b National Center for Nanoscience and Technology, Beijing 100190, P.R. China
E-mail: zytang@nanoctr.cn

c Graduate School of Chinese Academy of Sciences, Beijing 100049, P.R. China

Abstract

We applied force spectroscopy based on atomic force microscope (AFM) to demonstrate the possibility of measuring the interaction force between single quantum-dots (QDs) and living cells at single particle level under native conditions. In the force–distance cycle, we recorded the events of cellular uptake of single QDs and single QD detachment from the cell.

Graphical abstract: Recording force events of single quantum-dot endocytosis

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Article information

DOI
https://doi.org/10.1039/C1CC00040C
Article type
Communication
Submitted
04 Jan 2011
Accepted
27 Jan 2011
First published
15 Feb 2011

Chem. Commun., 2011,47, 3377-3379

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Recording force events of single quantum-dot endocytosis

Y. Shan, X. Hao, X. Shang, M. Cai, J. Jiang, Z. Tang and H. Wang, Chem. Commun., 2011, 47, 3377 DOI: 10.1039/C1CC00040C

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