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Issue 8, 2011
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A new linker for solid-phase synthesis of heparan sulfate precursors by sequential assembly of monosaccharide building blocks

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Abstract

A novel ester type linker which upon cleavage releases the glycans as carbamate protected aminoglycosides was successfully employed in the sequential assembly of L-idose and azido glucose monosaccharide building blocks to heparan sulfate precursors.

Graphical abstract: A new linker for solid-phase synthesis of heparan sulfate precursors by sequential assembly of monosaccharide building blocks

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Publication details

The article was received on 29 Oct 2010, accepted on 02 Dec 2010 and first published on 20 Dec 2010


Article type: Communication
DOI: 10.1039/C0CC04686H
Citation: Chem. Commun., 2011,47, 2390-2392
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    A new linker for solid-phase synthesis of heparan sulfate precursors by sequential assembly of monosaccharide building blocks

    P. Czechura, N. Guedes, S. Kopitzki, N. Vazquez, M. Martin-Lomas and N. Reichardt, Chem. Commun., 2011, 47, 2390
    DOI: 10.1039/C0CC04686H

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