Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules

Abstract

In recent years, gold nanoparticles (AuNPs) have drawn considerable research attention in the fields of catalysis, drug delivery, imaging, diagnostics, therapy and biosensors due to their unique optical and electronic properties. In this review, we summarized recent advances in the development of AuNP-based colorimetric and fluorescent assays for ions including cations (such as Hg²⁺, Cu²⁺, Pb²⁺, As³⁺, Ca²⁺, Al³⁺, etc) and anions (such as NO₂⁻, CN⁻, PF₆⁻, F⁻, I⁻, oxoanions), and small organic molecules (such as cysteine, homocysteine, trinitrotoluene, melamine and cocaine, ATP, glucose, dopamine and so forth). Many of these species adversely affect human health and the environment. Moreover, we paid particular attention to AuNP-based colorimetric and fluorescent assays in practical applications.