Issue 19, 2010
From the journal:

Chemical Communications

Seven-component reactions by sequential chemoselective Ugi–Mumm/Ugi–Smiles reactions†

Sebastian Brauch,ab   Lars Gabriela  and  Bernhard Westermann*ab  

* Corresponding authors

a Leibniz-Institute of Plant Biochemistry, Dept. of Bioorganic Chemistry, Weinberg 3, 06120 Halle, Germany
E-mail: bwesterm@ipb-halle.de
Fax: +49 345 55821340
Tel: +49 345 55821309

b Martin-Luther University Halle-Wittenberg, Department of Organic Chemistry, Kurt-Mothes-Str. 2, 06120 Halle, Germany

Abstract

A seven-component reaction was accomplished by utilizing the different chemoselectivities of the Ugi–Mumm and the Ugi–Smiles reaction. The sequential multicomponent reactions led to highly diverse peptide and glycopeptide like structures.

Graphical abstract: Seven-component reactions by sequential chemoselective Ugi–Mumm/Ugi–Smiles reactions

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Article information

DOI
https://doi.org/10.1039/B927388C
Article type
Communication
Submitted
05 Jan 2010
Accepted
01 Mar 2010
First published
19 Mar 2010

Chem. Commun., 2010,46, 3387-3389

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Seven-component reactions by sequential chemoselective Ugi–Mumm/Ugi–Smiles reactions

S. Brauch, L. Gabriel and B. Westermann, Chem. Commun., 2010, 46, 3387 DOI: 10.1039/B927388C

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