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Issue 19, 2010
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Oxygen-independent photonuclease activity of a new iron(ii) complex

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Abstract

A new iron(II) complex was synthesized and its photonuclease activity against plasmid DNA was evaluated. After kinetic experiments a kcat of 18.86 ± 2.9 h−1 was obtained, one of the highest nuclease activities of synthetic metallonucleases, selectively activated by 365 nm UV light.

Graphical abstract: Oxygen-independent photonuclease activity of a new iron(ii) complex

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Supplementary files

Article information


Submitted
28 Oct 2009
Accepted
01 Mar 2010
First published
18 Mar 2010

Chem. Commun., 2010,46, 3375-3377
Article type
Communication

Oxygen-independent photonuclease activity of a new iron(II) complex

B. de Souza, F. R. Xavier, R. A. Peralta, A. J. Bortoluzzi, G. Conte, H. Gallardo, F. L. Fischer, G. Bussi, H. Terenzi and A. Neves, Chem. Commun., 2010, 46, 3375
DOI: 10.1039/B922560A

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