Issue 19, 2010
From the journal:

Chemical Communications

Transformation of cytosine to uracil in single-stranded DNAvia their oxime sulfonates†

Yoshimi Oka,‡ab   Fumie Takeia  and  Kazuhiko Nakatani*a  

* Corresponding authors

a Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
E-mail: nakatani@sanken.osaka-u.ac.jp
Fax: +81-6-6879-8459
Tel: +81-6-6879-8459

b Career Design Laboratory for Women, Osaka University, 1-1 Yamadaoka, Suita, Osaka 567-0047, Japan

Abstract

The novel transformation of cytosine oxime sulfonate (C*) to uracil sulfonate (U*) proceeded by a CoII-assisted benzoyl peroxide reaction, eventually leading to the conversion of cytosine to uracil.

Graphical abstract: Transformation of cytosine to uracil in single-stranded DNA via their oxime sulfonates

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Article information

DOI
https://doi.org/10.1039/B920758A
Article type
Communication
Submitted
07 Oct 2009
Accepted
05 Mar 2010
First published
18 Mar 2010

Chem. Commun., 2010,46, 3378-3380

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Transformation of cytosine to uracil in single-stranded DNA via their oxime sulfonates

Y. Oka, F. Takei and K. Nakatani, Chem. Commun., 2010, 46, 3378 DOI: 10.1039/B920758A

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