Issue 10, 2009
From the journal:

Organic & Biomolecular Chemistry

Fluorescent organic nanoparticle formation in lysosomes for cancer cell recognition†

Hsin-Hung Lin,a   Sheng-Yuan Sua  and  Cheng-Chung Chang*a  

* Corresponding authors

a Department of Chemistry, National Chung Hsing University, 250, Kuo Kuang Road, Taichung, Taiwan, R.O.C
E-mail: ccchang555@dragon.nchu.edu.tw
Fax: +886-4-22862547

Abstract

We present a convenient method to prepare fluorophores 3- or 3,7-divinyl substituted 10H-phenothiazines and their protonation forms can aggregate to become fluorescent organic nanoparticles (FONs) with bright fluorescent spots in the lysosomes of cancer cells but not normal cells.

Graphical abstract: Fluorescent organic nanoparticle formation in lysosomes for cancer cell recognition

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Article information

DOI
https://doi.org/10.1039/B902399B
Article type
Communication
Submitted
05 Feb 2009
Accepted
27 Mar 2009
First published
07 Apr 2009

Org. Biomol. Chem., 2009,7, 2036-2039

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Fluorescent organic nanoparticle formation in lysosomes for cancer cell recognition

H. Lin, S. Su and C. Chang, Org. Biomol. Chem., 2009, 7, 2036 DOI: 10.1039/B902399B

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