Issue 10, 2009
From the journal:

Organic & Biomolecular Chemistry

Multivalent mannose-displaying nanoparticles constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]}†

Rongmin Su,a   Lei Li,b   Xiaoping Chen,a   Jiahuai Hanc  and  Shoufa Han*a  

* Corresponding authors

a Department of Chemistry, College of Chemistry and Chemical Engineering, and The Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, P. R. China
E-mail: shoufa@xmu.edu.cn

b College of Materials, Xiamen University, P. R. China

c College of Life Science, Xiamen University, P. R. China

Abstract

Micellar mannose nanoparticles were constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]} with fluorophores or quenchers doped into the hydrophobic inner cores, allowing the direct monitoring of multivalent lectin–glycan interactions. The mannose-displaying nanoparticles bind Con A and sperm surface lectins with high affinity, suggesting their broad utility for modulating protein–carbohydrate interaction mediated cell surface biology.

Graphical abstract: Multivalent mannose-displaying nanoparticles constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]}

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B817823B
Article type
Paper
Submitted
10 Oct 2008
Accepted
04 Dec 2008
First published
17 Mar 2009

Org. Biomol. Chem., 2009,7, 2040-2045

Permissions

Request permissions

Multivalent mannose-displaying nanoparticles constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]}

R. Su, L. Li, X. Chen, J. Han and S. Han, Org. Biomol. Chem., 2009, 7, 2040 DOI: 10.1039/B817823B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements