Issue 12, 2009
From the journal:

Natural Product Reports

The chemistry and biology of LL-37

Matthew F. Burtona  and  Patrick G. Steel*a  

* Corresponding authors

a Centre for Bioactive Chemistry, Department of Chemistry, University of Durham, Science Laboratory, South Road, Durham, UK
E-mail: m.f.burton@durham.ac.uk, p.g.steel@durham.ac.uk
Fax: +44(0)191 384 4737
Tel: +44(0)191 334 2131

Abstract

Covering: up to June 2009

LL-37 is a human host defence peptide that has a wide range of biological functions, including antimicrobial and immunomodulatory properties. This review summarises how molecular structure influences the balance between the immunomodulatory and antimicrobial functions of LL-37.

Graphical abstract: The chemistry and biology of LL-37

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Article information

DOI
https://doi.org/10.1039/B912533G
Article type
Review Article
Submitted
29 Jun 2009
First published
01 Oct 2009

Nat. Prod. Rep., 2009,26, 1572-1584

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The chemistry and biology of LL-37

M. F. Burton and P. G. Steel, Nat. Prod. Rep., 2009, 26, 1572 DOI: 10.1039/B912533G

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