Issue 12, 2009
From the journal:

Natural Product Reports

Chemo-enzymatic synthesis and functional analysis of natural and modified glycostructures

Arne Homanna  and  Jürgen Seibel*a  

* Corresponding authors

a Department of Organic Chemistry, University of Würzburg, Am Hubland, Würzburg, Germany
E-mail: seibel@chemie.uni-wuerzburg.de
Fax: +49 931 8884606
Tel: +49 931 3185326

Abstract

Covering: 2006 to 2009

The advancing field of glycomics is driven by the development of new analysis and synthesis techniques and novel strategies such as metabolic glyco-labeling. In this review we will present strategies for tailoring chemo-emzymatic glycosyltransfer reactions, screening methods such as carbohydrate-based micro-arrays, and metabolic glyco-engineering as a strategy to visualize biological recognition processes for the development of carbohydrate-based vaccines.

Graphical abstract: Chemo-enzymatic synthesis and functional analysis of natural and modified glycostructures

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Article information

DOI
https://doi.org/10.1039/B909990P
Article type
Review Article
Submitted
06 Aug 2009
First published
22 Oct 2009

Nat. Prod. Rep., 2009,26, 1555-1571

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Chemo-enzymatic synthesis and functional analysis of natural and modified glycostructures

A. Homann and J. Seibel, Nat. Prod. Rep., 2009, 26, 1555 DOI: 10.1039/B909990P

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