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Issue 20, 2009
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Transcription of an RNA aptamer by a DNA polymerase

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Abstract

Therminator DNA polymerase, a variant of the 9°N DNA polymerase, is shown to synthesize a functional RNA aptamer; thus providing a simple route for making DNA-tagged RNA aptamers for use in DNA nanotechnology.

Graphical abstract: Transcription of an RNA aptamer by a DNA polymerase

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Publication details

The article was received on 19 Nov 2008, accepted on 20 Feb 2009 and first published on 06 Apr 2009


Article type: Communication
DOI: 10.1039/B820678C
Citation: Chem. Commun., 2009,0, 2938-2940
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    Transcription of an RNA aptamer by a DNA polymerase

    E. O. McCullum and J. C. Chaput, Chem. Commun., 2009, 0, 2938
    DOI: 10.1039/B820678C

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