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Issue 1, 2008

A microwave assisted intramolecular-furan-Diels–Alder approach to 4-substituted indoles

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Abstract

The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an α-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels–Alder cycloaddition and an in situ double aromatization reaction.

Graphical abstract: A microwave assisted intramolecular-furan-Diels–Alder approach to 4-substituted indoles

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Publication details

The article was received on 29 Sep 2008, accepted on 30 Oct 2008 and first published on 11 Nov 2008


Article type: Communication
DOI: 10.1039/B816989F
Citation: Chem. Commun., 2008,0

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    A microwave assisted intramolecular-furan-Diels–Alder approach to 4-substituted indoles

    F. Petronijevic, C. Timmons, A. Cuzzupe and P. Wipf, Chem. Commun., 2008, 0
    DOI: 10.1039/B816989F

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