Issue 3, 2008
From the journal:

Chemical Communications

Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation†

Claire Kaiser,a   Giselle Segui-Lines,a   Jason C. D'Amaral,a   Adam S. Ptolemya  and  Philip Britz-McKibbin*a  

* Corresponding authors

a Department of Chemistry, McMaster University, Hamilton, ON, Canada
E-mail: britz@mcmaster.ca
Fax: +1-905-522-2509
Tel: +1-905-525-9140

Abstract

Electrokinetic probes based on the differential migration of ternary boronate ester complexes permit the selective analysis of micromolar levels of UV-transparent polyol stereoisomers in urine samples via dynamic complexation–capillary electrophoresis that is applicable to single-step screening of in-born errors of sugarmetabolism, such as galactosemia.

Graphical abstract: Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation

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Article information

DOI
https://doi.org/10.1039/B714215C
Article type
Communication
Submitted
14 Sep 2007
Accepted
16 Oct 2007
First published
26 Oct 2007

Chem. Commun., 2008, 338-340

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Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation

C. Kaiser, G. Segui-Lines, J. C. D'Amaral, A. S. Ptolemy and P. Britz-McKibbin, Chem. Commun., 2008, 338 DOI: 10.1039/B714215C

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