Issue 46, 2007
From the journal:

Chemical Communications

Nornicotine-organocatalyzed aqueous reduction of α,β-unsaturated aldehydes†

Andrew P. Brogan,a   Tobin J. Dickerson*b  and  Kim D. Janda*a  

* Corresponding authors

a Departments of Chemistry and Immunology, Skaggs Institute for Chemical Biology, & Worm Institute for Research and Medicine (WIRM), The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
E-mail: kdjanda@scripps.edu

b Department of Chemistry & Worm Institute for Research and Medicine (WIRM), The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
E-mail: tobin@scripps.edu

Abstract

Nornicotine, a native component of tobacco and minor nicotinemetabolite, was found to catalyze the chemoselective reduction of α,β-unsaturated aldehydes under homogeneous aqueous conditions.

Graphical abstract: Nornicotine-organocatalyzed aqueous reduction of α,β-unsaturated aldehydes

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Article information

DOI
https://doi.org/10.1039/B713273E
Article type
Communication
Submitted
29 Aug 2007
Accepted
22 Sep 2007
First published
09 Oct 2007

Chem. Commun., 2007, 4952-4954

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Nornicotine-organocatalyzed aqueous reduction of α,β-unsaturated aldehydes

A. P. Brogan, T. J. Dickerson and K. D. Janda, Chem. Commun., 2007, 4952 DOI: 10.1039/B713273E

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