Issue 45, 2007
From the journal:

Chemical Communications

Palladium-catalysed N-annulation routes to indoles: the synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1†

Anthony J. Fletcher,a   Matthew N. Baxb  and  Michael C. Willis*a  

* Corresponding authors

a Department of Chemistry, University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford, UK
E-mail: michael.willis@chem.ox.ac.uk
Fax: +44 (0)1865 285002
Tel: +44 (0)1865 285126

b Department of Chemistry, University of Bath, Bath, UK

Abstract

Tandem palladium-catalysed aryl and alkenyl C–N bond formation allows the synthesis of a variety of indoles bearing sterically demanding N-substituents, including the natural product demethylasterriquinone A1.

Graphical abstract: Palladium-catalysed N-annulation routes to indoles: the synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1

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Article information

DOI
https://doi.org/10.1039/B712227F
Article type
Communication
Submitted
08 Aug 2007
Accepted
20 Aug 2007
First published
03 Sep 2007

Chem. Commun., 2007, 4764-4766

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Palladium-catalysed N-annulation routes to indoles: the synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1

A. J. Fletcher, M. N. Bax and M. C. Willis, Chem. Commun., 2007, 4764 DOI: 10.1039/B712227F

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