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Issue 46, 2007
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Scaffolded amino acids as a close structural mimic of type-3 copper binding sites

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Abstract

We report the use of triazacyclophane (TAC)-scaffolded amino acids as a structural mimic for 3-histidine metal-binding sites in metalloproteins, especially for the mimicry of type-3 copper binding sites as are present in hemocyanin, tyrosinase and catechol oxidase.

Graphical abstract: Scaffolded amino acids as a close structural mimic of type-3 copper binding sites

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Article information


Submitted
20 Jun 2007
Accepted
18 Oct 2007
First published
02 Nov 2007

Chem. Commun., 2007, 4895-4897
Article type
Communication

Scaffolded amino acids as a close structural mimic of type-3 copper binding sites

H. B. Albada, F. Soulimani, B. M. Weckhuysen and R. M. J. Liskamp, Chem. Commun., 2007, 4895
DOI: 10.1039/B709400K

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