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Issue 27, 2007
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The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS)

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Abstract

New findings lead to a revised understanding of the substrates' binding order, the role of the substrate as an activator, and the observed lag phase in the FDTS catalyzed reaction.

Graphical abstract: The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS)

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Article information


Submitted
22 Jan 2007
Accepted
10 Apr 2007
First published
25 Apr 2007

Chem. Commun., 2007, 2861-2863
Article type
Communication

The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS)

A. Chernyshev, T. Fleischmann, E. M. Koehn, S. A. Lesley and A. Kohen, Chem. Commun., 2007, 2861
DOI: 10.1039/B700977A

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